Protecting global
travelers from malaria

For individuals traveling to endemic areas, ARAKODA® (tafenoquine) tablets are indicated for the prophylaxis of malaria in patients aged 18 years and older.1

The Annual Burden of Malaria

25-30 million travelers visit malaria-endemic tropic and subtropic regions2

About 250 million cases in 85 countries and over 600,000 deaths3*

About 2,000 cases in the United States, mostly from travelers returning from sub-Saharan Africa and South Asia4

A new standard of care with ARAKODA

The only prophylactic therapy to provide protection against all stages of malaria1

Recommended for travelers by CDC5

Convenient weekly dosing1†

Established safety profile1

CDC = Centers for Disease Control and Prevention.
*Based on 2022 data.
†With one dose upon return from traveling. Please see Prescribing Information and dosing instructions.

View the ARAKODA Product Monograph

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Fulfilling the Promise of ARAKODA

With promising new data, 60 Degrees Pharma is seeking to evaluate the utility of tafenoquine for the following indications:

Tafenoquine Pipeline

Treatment of Babesiosis*

Tafenoquine exhibits useful activity in animal models of babesiosis and may have clinical utility in treatment of drug-resistant strains. A proof-of-concept clinical study is planned to assess the utility of ARAKODA as a treatment for human babesiosis.

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Treatment and Prevention of Fungal Diseases*

In vitro and in vivo studies demonstrate that tafenoquine is effective for treatment and prevention of fungi such as Pneumocystis and yeasts at doses that are clinically relevant.6

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*ARAKODA has not been reviewed or approved by the U.S. Food and Drug Administration for the treatment or prevention of babesiosis or fungal diseases.

References: 1. Arakoda® [package insert]. 60 Degrees Pharmaceuticals LLC: 2021. 2. Angelo KM, Libman M, Caumes E, et al. Malaria after international travel: a GeoSentinel analysis, 2003-2016. Malar J. 2017;16(1):293. doi:10.1186/s12936-017-1936-3 3. World Health Organization. Malaria fact sheet. Updated December 4, 2023. Accessed March 7, 2024. https://www.who.int/news-room/fact-sheets/detail/malaria 4. Centers for Disease Control and Prevention. Malaria. Reviewed August 18, 2023. Accessed March 7, 2024. https://www.cdc.gov/parasites/malaria/index.html 5. Centers for Disease Control and Prevention. Choosing a drug to prevent malaria. Reviewed February 1, 2023. Accessed March 7, 2024. https://www.cdc.gov/malaria/travelers/drugs.html 6. Dow GS, Smith BL. Tafenoquine exhibits broad spectrum antifungal activity at clinically relevant concentrations in vitro and decreases lung fungal burden in an invasive pulmonary model of Rhizopus in vivo. New Microbes New Infect. 2022;45:100964. doi:10.1016/j.nmni.2022.100964